Short-Term High Fat Intake Does Not Significantly Alter Markers of Renal Function or Inflammation in Young Male Sprague-Dawley Rats
Table 2
Plasma and urinary markers of renal functionand damage.
Measure
Chow ()
HFD ()
value
Urine creatinine (mg/L)
765.0 ± 110.6 (8)
900.3 ± 137.4 (8)
0.456
Urine protein : creatinine ratio (AU)
6.01 ± 2.86 (8)
3.89 ± 1.31 (8)
0.574
Urine H2O2 (pM/µL)
0.023 ± 0.003 (6)
0.048 ± 0.005 (6)
0.002
Urine H2O2 : creatinine ratio (AU)
0.014 ± 0.002 (6)
0.026 ± 0.007 (6)
0.142
Plasma cystatin C (g/mL)
14.35 ± 0.99 (10)
16.2 ± 1.12 (10)
0.233
Renal TBARS (mM/L)
26.9 ± 2.02 (5)
28.08 ± 0.80 (5)
0.600
Plasma oxDNA/RNA (pg/mL)
887 ± 145 (10)
1003 ± 188 (11)
0.634
Data expressed as mean ± SEM and analyzed by Student’s -tests with the exception of urine protein : creatinine ratio, which was analyzed by the Mann-Whitney test.