Research Article

Short-Term High Fat Intake Does Not Significantly Alter Markers of Renal Function or Inflammation in Young Male Sprague-Dawley Rats

Table 2

Plasma and urinary markers of renal functionand damage.

MeasureChow ()HFD () value

Urine creatinine (mg/L)765.0 ± 110.6 (8)900.3 ± 137.4 (8)0.456
Urine protein : creatinine ratio (AU)6.01 ± 2.86 (8)3.89 ± 1.31 (8)0.574
Urine H2O2 (pM/µL)0.023 ± 0.003 (6)0.048 ± 0.005 (6)0.002
Urine H2O2 : creatinine ratio (AU)0.014 ± 0.002 (6)0.026 ± 0.007 (6)0.142
Plasma cystatin C (g/mL)14.35 ± 0.99 (10)16.2 ± 1.12 (10)0.233
Renal TBARS (mM/L)26.9 ± 2.02 (5)28.08 ± 0.80 (5)0.600
Plasma oxDNA/RNA (pg/mL)887 ± 145 (10)1003 ± 188 (11)0.634

Data expressed as mean ± SEM and analyzed by Student’s -tests with the exception of urine protein : creatinine ratio, which was analyzed by the Mann-Whitney test.