Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer

Table 1

Active Holistic Surveillance supplements.

Supplement	Directions	Rationale	Citations
BroccoProtect	3 capsules, daily	(i) Rich in glucosinolates and antioxidants; (ii) Neutralizes the effect of heterocyclic amines found in meats; (iii) Induces the apoptosis of prostate cancer cells and prohibits these cells from proliferating; (iv) Protects somatic DNA from carcinogenic damage	[6–8]
Omega 3	2000 mg, daily	(i) Suppresses inflammation; (ii) Inhibits growth factor induced proliferation in prostate cancer cells	[9, 10]
Zyflamend	3 capsules, daily	(i) Suppresses inflammation; (ii) Reduces growth of prostate cell lines; (iii) Induces apoptosis of prostate cancer cells	[11, 12]
Vitamin D3	5000 IU, daily	(i) Promotes differentiation of prostate cancer cells; (ii) Induces apoptosis of prostate cancer cells; (iii) Attenuates proliferation	[13–15]
Genikinoko (GCP)	1000 mg, twice daily	(i) Rich in genistein; (ii) Causes cell cycle growth arrest; (iii) Induces apoptosis of prostate cancer cells; (iv) Antiangiogenesis properties in vitro and in vivo; (v) Reduces serum PSA	[6, 16–19]
Active Hexose Correlated Compound (AHCC)	3 capsules, daily	(i) Boosts host immunity; (ii) Protects against disorders induced by oxidative stress; (iii) Reduces serum PSA	[20–24]
Lycocell	2 capsules, daily	(i) Lycopene complex; (ii) Antioxidants protect DNA from damage; (iii) Causes prostate cancer cell cycle arrest and apoptosis; (iv) Induces differentiation; (v) Reduces oxidative stress	[25, 26]