Hepatoprotective Activity of Herbal Composition SAL, a Standardize Blend Comprised of Schisandra chinensis, Artemisia capillaris, and Aloe barbadensis

Table 3

Effect of SAL (300 mg/kg) on the major biomarkers of liver in APAP model.

Group	Material dose (mg/kg)		Survival rate	Analyte
				AST (U/L)	Bile acid (μmol/L)	T. bilirubin (mg/dL)	Albumin (g/dL)	T. protein (g/dL)
Control	0	10	100	77.7 ± 28.3	1.0 + 0.0	0.1 + 0.0	2.67 + 0.09	4.70 + 0.24
APAP (400 mg/kg)	0	10	60	4707.7 ± 2899.1	76.2 + 24.8	0.5 + 0.2	2.33 + 0.20	4.43 + 0.22
SAL	300	10	90	1855.7 ± 1859.6	15.1 + 5.7	0.3 + 0.1	2.71 + 0.12	4.84 + 0.12

Mice () were orally given composition SAL at doses of 300 mg/kg at −48 hr, −24 hr, and −2 hr before APAP administrations and +6 hr after induction of model suspended in 10% Tween-20. Hepatotoxicity models were induced using 400 mg/kg APAP administered orally. Serum was collected at T24. Data are expressed as mean ± SD. .