Omega-3 Fatty Acids: Possible Neuroprotective Mechanisms in the Model of Global Ischemia in Rats

Figure 7

3 treatments of ischemic animals (3 animals per group) reduced the immunostaining for COX-2, mainly in the dentate gyrus (DG) and hilus. Representative photomicrographs and quantitative measurements performed with the Image J software, from 3 to 5 fields. The groups are untreated ischemic (ISC) and ischemic after treatments with 3 (2.5 and 10 mg/kg, 7 days). DG: (A) versus SO, q = ; (B) versus ISC + 3 (2.5), q = ; (C) versus ISC + ω3 (10), q = . Hilus: (A) versus SO, q = ; (B) versus ISC + 3 (2.5), q = ; (C) versus ISC + ω3 (10), q = ; (D) versus SO, q = ; (E) versus SO, q = (one-way ANOVA and Newman-Keuls test as the post hoc test).