Absorption, Metabolism, and Excretion by Freely Moving Rats of 3,4-DHPEA-EDA and Related Polyphenols from Olive Fruits (Olea europaea)

Table 1

Identification of metabolites from plasma, urine, and bile after administration of 3,4-DHPEA-EDA, hydroxytyrosol, and oleuropein.

Rt (min)	(nm)	Formula	Calc. mass [M−H]^−	Observed [M−H]^−	Mass error (mDa)	Compound identification
3.96	230, 278	C8H10O3	153.0552	153.0554	0.2	Hydroxytyrosol
8.95	228, 278	C8H12O3	167.0708	167.0731	2.3	Homovanillyl alcohol
9.67	230, 278	C9H10O4	181.0501	181.0533	3.2	Homovanillic acid
20.10	230, 280	C25H32O8	539.1765	539.1776	1.1	Oleuropein

Data was obtained from HT metabolites isolated from urine.
Data was obtained from oleuropein isolated from plasma.