Amino Acid Medical Foods Provide a High Dietary Acid Load and Increase Urinary Excretion of Renal Net Acid, Calcium, and Magnesium Compared with Glycomacropeptide Medical Foods in Phenylketonuria

<div>Renal net acid excretion (a), urinary calcium excretion (b), urinary magnesium excretion (c), and urinary sulfate excretion (d), based on 24-hr urine collections in participants with PKU who consumed AA-MF or GMP-MF,<i> n</i> = 8. Values are means ± SE. The dashed lines (b, c, d) represent the reference range for urinary calcium excretion (100–300 mg/d), magnesium excretion (12–293 mg/d), and urinary sulfate excretion (0–30 mEq/d). Results indicate significant increases in renal net acid excretion (<i>p </i>= 0.002), urinary calcium (<i>p</i> = 0.012), magnesium (<i>p </i>= 0.029), and sulfate (<i>p</i> = 0.0008) excretion with AA-MF compared to GMP-MF. AA-MF, amino acid medical foods; GMP-MF, glycomacropeptide medical foods.</div>

Journal of Nutrition and Metabolism

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Figure 2

Figure 2: Amino Acid Medical Foods Provide a High Dietary Acid Load and Increase Urinary Excretion of Renal Net Acid, Calcium, and Magnesium Compared with Glycomacropeptide Medical Foods in Phenylketonuria 

Figure 2 | Amino Acid Medical Foods Provide a High Dietary Acid Load and Increase Urinary Excretion of Renal Net Acid, Calcium, and Magnesium Compared with Glycomacropeptide Medical Foods in Phenylketonuria 