Diet-Induced Obesity Is Associated with an Impaired NK Cell Function and an Increased Colon Cancer Incidence

Figure 2

Influence of leptin on the mRNA expression of the activating NK cell receptors Klrk1/NKG2D (a, d), Ncr1/NKp46 (b, e), and Ncr3/NKp30 (c, f). NK-92 cells were incubated in the absence or presence of 10 ng/mL (L10) or 100 ng/mL (L100) leptin for 4 h (a–c) or 24 h (d–e). Results are expressed as the mean ± SEM fold-change compared to control cells, from three individual experiments with each well. , , and compared to control cells.

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