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Journal of Nutrition and Metabolism
Volume 2017 (2017), Article ID 4823102, 7 pages
Research Article

The Effect of Exercise Intensity on Total PYY and GLP-1 in Healthy Females: A Pilot Study

1Department of Kinesiology and Physical Education, University of Lethbridge, Lethbridge, AB, Canada T1K 3M4
2Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, ON, Canada N2L 3C5

Correspondence should be addressed to Tom J. Hazell

Received 12 July 2016; Revised 4 October 2016; Accepted 19 January 2017; Published 13 February 2017

Academic Editor: Maurizio Muscaritoli

Copyright © 2017 Jillian R. Hallworth et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We compared the acute response of anorexigenic signals (total PYY and GLP-1) in response to submaximal and supramaximal exercise. Nine females completed three sessions: (1) moderate-intensity continuous training (MICT; 30 min; 65%  ); (2) sprint interval training (SIT; 6 × 30 sec “all-out” cycling sprints with 4 min recovery); or (3) control (CTRL; no exercise). PYY and GLP-1 were measured via blood samples drawn before, immediately after, and 90 min after exercise. Perceptions of hunger were rated using a visual analogue scale at all blood sampling time points. There was a session × time interaction for GLP-1 () where SIT and MICT ( and ) were higher compared to CTRL both immediately and 90 min after exercise. There was a main effect of time for PYY where 90 min after exercise it was decreased versus before and immediately after exercise. There was a session × time interaction for hunger with lower ratings following SIT versus MICT () and CTRL () 90 min after exercise. These results suggest that though GLP-1 is elevated after exercise in women, it is not affected by exercise intensity though hunger was lower 90 min after exercise with SIT. As the sample size is small further study is needed to confirm these findings.