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Journal of Nutrition and Metabolism
Volume 2018, Article ID 4384012, 11 pages
https://doi.org/10.1155/2018/4384012
Research Article

Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells

1Department of Food Technology and Science, Center of Rural Sciences, Federal University of Santa Maria (UFSM), 1000 Roraima Avenue, 97105-900 Santa Maria, RS, Brazil
2Department of Chemical Engineering, Center of Technology, Federal University of Santa Maria (UFSM), 1000 Roraima Avenue, 97105-900 Santa Maria, RS, Brazil
3Department of Biochemistry, Center of Oxidative Stress Research (CEEO), Federal University of Rio Grande do Sul (UFRGS), 2600 Ramiro Barcelos Street–Annex, 90035-003 Porto Alegre, RS, Brazil

Correspondence should be addressed to Cristiane Copetti; moc.liamg@sirc.ittepoc

Received 4 September 2017; Accepted 30 November 2017; Published 1 March 2018

Academic Editor: Michael B. Zemel

Copyright © 2018 Cristiane Copetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Halliwell, “Free radicals and antioxidants–quo vadis?” Trends in Pharmacological Sciences, vol. 32, no. 3, pp. 125–130, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Lee, S. Giordano, and J. Zhang, “Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling,” Biochemical Journal, vol. 441, no. 2, pp. 523–540, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Halliwell, “Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life,” Plant Physiology, vol. 141, no. 2, pp. 312–322, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Valko, D. Leibfritz, J. Moncol, M. T. D. Cronin, M. Mazur, and J. Telser, “Free radicals and antioxidants in normal physiological functions and human disease,” International Journal of Biochemistry and Cell Biology, vol. 39, no. 1, pp. 44–84, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. N. Kardum, M. Takić, K. Šavikin et al., “Effects of polyphenol-rich chokeberry juice on cellular antioxidant enzymes and membrane lipid status in healthy women,” Journal of Functional Foods, vol. 9, pp. 89–97, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. F. L. Crowe, A. W. Roddam, T. J. Key et al., “Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study,” European Heart Journal, vol. 32, no. 10, pp. 1235–1243, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. J. F. D. C. Guerra, P. S. Maciel, I. C. M. E. de Abreu et al., “Dietary açaí attenuates hepatic steatosis via adiponectin-mediated effects on lipid metabolism in high-fat diet mice,” Journal of Functional Foods, vol. 14, pp. 192–202, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. M. N. Clifford, “Chlorogenic acids and other cinnamates–nature, occurrence, dietary burden, absorption and metabolism,” Journal of the Science of Food and Agriculture, vol. 80, no. 7, pp. 1033–1043, 2000. View at Publisher · View at Google Scholar
  9. K. B. Pandey and S. I. Rizvi, “Markers of oxidative stress in erythrocytes and plasma during aging in humans,” Oxidative Medicine and Cellular Longevity, vol. 3, no. 1, pp. 2–12, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Bagchi, M. Bagchi, S. J. Stohs et al., “Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention,” Toxicology, vol. 148, no. 2-3, pp. 187–197, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Sano, R. Uchida, M. Saito et al., “Beneficial effects of grape seed extract on malondialdehyde-modified LDL,” Journal of Nutritional Science and Vitaminology, vol. 53, no. 2, pp. 174–182, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. I. C. Arts and P. C. Hollman, “Polyphenols and disease risk in epidemiologic studies,” American Journal of Clinical Nutrition, vol. 81, no. 1, pp. 317S–325S, 2005. View at Google Scholar
  13. D. Kammerer, A. Claus, R. Carle, and A. Schieber, “Polyphenol screening of pomace from red and white grape varieties (Vitis vinifera L.) by HPLC-DAD-MS/MS,” Journal of Agricultural and Food Chemistry, vol. 52, no. 14, pp. 4360–4367, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Y. Sun, Q. Wang, A. Simonyi, and G. Y. Sun, “Botanical phenolics and brain health,” NeuroMolecular Medicine, vol. 10, no. 4, pp. 259–274, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. I. M. Toaldo, F. A. Cruz, T. L. Alves et al., “Bioactive potential of Vitis labrusca L. grape juices from the Southern Region of Brazil: phenolic and elemental composition and effect on lipid peroxidation in healthy subjects,” Food Chemistry, vol. 173, pp. 527–535, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. P. Castilla, R. Echarri, A. Dávalos et al., “Concentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjects,” American Journal of Clinical Nutrition, vol. 84, no. 1, pp. 252–262, 2006. View at Google Scholar
  17. C. Dani, L. S. Oliboni, R. Vanderlinde, D. Bonatto, M. Salvador, and J. A. P. Henriques, “Phenolic content and antioxidant activities of white and purple juices manufactured with organically or conventionally produced grapes,” Food and Chemical Toxicology, vol. 45, no. 12, pp. 2574–2580, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. I. M. Toaldo, F. A. Cruz, E. L da Silva, and M. T. Bordignon-Luiz, “Acute consumption of organic and conventional tropical grape juices (Vitis labrusca L.) increases antioxidants in plasma and erythrocytes, but not glucose and uric acid levels, in healthy individuals,” Nutrition Research, vol. 36, no. 8, pp. 808–817, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. C. R. Pace-Asciak, O. Rounova, S. E. Hahn, E. P. Diamandis, and D. M. Goldberg, “Wines and grape juices as modulators of platelet aggregation in healthy human subjects,” Clinica Chimica Acta, vol. 246, no. 1-2, pp. 163–182, 1996. View at Publisher · View at Google Scholar · View at Scopus
  20. S. R. Coimbra, S. H. Lage, L. Brandizzi, V. Yoshida, and P. L. da Luz, “The action of red wine and purple grape juice on vascular reactivity is independent of plasma lipids in hypercholesterolemic patients,” Brazilian Journal of Medical and Biological Research, vol. 38, no. 9, pp. 1339–1347, 2005. View at Publisher · View at Google Scholar
  21. F. A. van Dorsten, C. H. Grun, E. J. van Velzen, D. M. Jacobs, R. Draijer, and J. P. van Duynhoven, “The metabolic fate of red wine and grape juice polyphenols in humans assessed by metabolomics,” Molecular Nutrition and Food Research, vol. 54, no. 7, pp. 897–908, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. V. M. Burin, N. E. Ferreira-Lima, C. P. Panceri, and M. T. Bordignon-Luiz, “Bioactive compounds and antioxidant activity of Vitis vinifera and Vitis labrusca grapes: evaluation of different extraction methods,” Microchemical Journal, vol. 114, pp. 155–163, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. L. A. Rizzon and M. Link, “Composição do suco de uva caseiro de diferentes cultivares,” Ciência Rural, vol. 36, no. 2, pp. 689–692, 2006. View at Publisher · View at Google Scholar
  24. P. Pszczólkowski and C. C. de Lecco, Manual de Vinificación: Guía práctica para la elaboración de vinos,, E. U. C. de Chile Ed., Chile: Ediciones Universidad católica de Chile, Santiago, Chile, 1a edition, 2011.
  25. V. L. Singleton and J. A. Rossi, “Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents,” American Journal of Enology and Viticulture, vol. 16, pp. 144–158, 1965. View at Google Scholar
  26. P. Ribéreau-Gayon and E. Stonestreet, “Le dosage dês antocyanes dans le vin rouge,” Bulletin de la Société Chimique de France, vol. 9, pp. 2649–2652, 1965. View at Google Scholar
  27. J. Zhishen, T. Mengcheng, and W. Jianming, “The determination of flavonoid contents in mulberry and the scavenging effects on superoxide radicals,” Food Chemistry, vol. 64, no. 4, pp. 555–559, 1999. View at Publisher · View at Google Scholar · View at Scopus
  28. R. Re, N. Pellegrini, A. Proteggemnte, A. Pannala, M. Yang, and C. Rice-Evans, “Antioxidant activity applying and improved ABTS radical cation decolorization assay,” Free Radical Biology and Medicine, vol. 26, no. 9-10, pp. 1234–1237, 1999. View at Publisher · View at Google Scholar · View at Scopus
  29. I. F. F. Benzie and J. J. Strain, “The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay,” Analytical Biochemistry, vol. 239, no. 1, pp. 70–76, 1996. View at Publisher · View at Google Scholar · View at Scopus
  30. C. Manach, A. Scalbert, C. Morand, C. Rémésy, and L. Jiménez, “Polyphenols: food sources and bioavailability,” American Journal of Clinical Nutrition, vol. 79, no. 5, pp. 727–747, 2004. View at Google Scholar
  31. H. Ohkawa, N. Ohishi, and K. Yagi, “Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction,” Analytical Biochemistry, vol. 95, no. 2, pp. 351–358, 1979. View at Publisher · View at Google Scholar · View at Scopus
  32. H. Wang and J. A. Joseph, “Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader,” Free Radical Biology and Medicine, vol. 27, no. 5-6, pp. 612–616, 1999. View at Publisher · View at Google Scholar · View at Scopus
  33. T. K. Rabelo, F. Zeidán-Chuliá, and L. M. Vasques, “Redox characterization of usnic acid and its cytotoxic effect on human neuron-like cells (SH-SY5Y),” Toxicology in Vitro, vol. 26, no. 2, pp. 304–314, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. D. P. Gelain and J. C. Moreira, “Evidence of increased reactive species formation by retinol, but not retinoic acid, in PC12 cells,” Toxicology in Vitro, vol. 22, no. 3, pp. 553–558, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Ferrari, M. C. Fornasiero, and A. M. Isetta, “MTT colorimetric assay for testing macrophage cytotoxic activity in vitro,” Journal of Immunological Methods, vol. 131, no. 2, pp. 165–172, 1990. View at Publisher · View at Google Scholar · View at Scopus
  36. M. V. B. Malachias, W. K. S. B. Souza, F. L. Plavnik et al., “7a Diretriz Brasileira de Hipertensão Arterial,” Arquivos Brasileiros de Cardiologia, vol. 107, no. 3, pp. 1–83, 2016. View at Google Scholar
  37. P. A. James, S. Oparil, B. L. Carter et al., “2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8),” JAMA, vol. 311, no. 5, pp. 507–520, 2014. View at Publisher · View at Google Scholar · View at Scopus
  38. C. Manach, A. Mazur, and A. Scalbert, “Polyphenols and prevention of cardiovascular diseases,” Current Opinion in Lipidology, vol. 16, no. 1, pp. 77–84, 2005. View at Publisher · View at Google Scholar
  39. M. Seruga, Y. Novak, and L. Jakobek, “Determination of polyphenols content and antioxidant activity of some red wines by differential pulse voltammetry, HPLC and spectrophotometric methods,” Food Chemistry, vol. 124, no. 3, pp. 1208–1216, 2011. View at Publisher · View at Google Scholar · View at Scopus
  40. M. V. Baroni, D. P. N. Romina, C. García-Ferreyra, S. Otaiza, and D. A. Wunderlin, “How good antioxidant is the red wine? Comparison of some in vitro and in vivo methods to assess the antioxidant capacity of Argentinean red wines,” LWT-Food Science and Technology, vol. 47, no. 1, pp. 1–7, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. G. Ruberto, A. Renda, C. Daquino et al., “Polyphenol constituents and antioxidant activity of grape pomace extracts from five Sicilian red grape cultivars,” Food Chemistry, vol. 100, no. 1, pp. 203–210, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. I. I. Rockenbach, E. Rodrigues, L. V. Gonzaga et al., “Phenolic compounds content and antioxidant activity in pomace from selected red grapes (Vitis vinifera L. and Vitis labrusca L.) widely produced in Brazil,” Food Chemistry, vol. 127, no. 1, pp. 174–179, 2011. View at Publisher · View at Google Scholar · View at Scopus
  43. N. Nenadis, O. Lazaridou, and M. Z. Tsimidou, “Use of reference compounds in antioxidant activity assessment,” Journal of Agricultural and Food Chemistry, vol. 55, no. 14, pp. 5452–5460, 2007. View at Publisher · View at Google Scholar · View at Scopus
  44. J. Pérez-Jiménez, J. Serrano, M. Tabernero et al., “Effects of grape antioxidant dietary fiber in cardiovascular disease risk factors,” Nutrition, vol. 24, no. 7-8, pp. 646–653, 2008. View at Publisher · View at Google Scholar · View at Scopus
  45. Y. Dotan, D. Lichtenberg, and I. Pinchuk, “Lipid peroxidation cannot be used as a universal criterion of oxidative stress,” Progress in Lipid Research, vol. 43, no. 3, pp. 200–227, 2004. View at Publisher · View at Google Scholar · View at Scopus
  46. K. Moore and L. J. Roberts, “Measurement of lipid peroxidation,” Free Radical Research, vol. 28, no. 6, pp. 659–671, 1998. View at Publisher · View at Google Scholar
  47. J. García-Alonso, G. Rosa, L. Vidal-Guevara, and M. J. Periago, “Acute intake of phenolic-rich juice improves antioxidant status in healthy subjects,” Nutrition Research, vol. 26, no. 7, pp. 330–339, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. G. K. Vieira, P. F. Di Pietro, E. L. da Silva, G. S. C. Borges, E. C. Nunes, and R. Fett, “Improvement of serum antioxidant status in humans after the acute intake of apple juices,” Nutrition Research, vol. 32, no. 3, pp. 229–232, 2012. View at Publisher · View at Google Scholar · View at Scopus
  49. A. L. Cardoso, P. F. Di Pietro, F. G. K. Vieira et al., “Acute consumption of juçara juice (Euterpe edulis) and antioxidant activity in healthy individuals,” Journal of Functional Foods, vol. 17, pp. 152–162, 2015. View at Publisher · View at Google Scholar · View at Scopus
  50. E. F. Gris, F. Mattivi, E. A. Ferreira et al., “Phenolic profile and effect of regular consumption of Brazilian red wines on in vivo antioxidant activity,” Journal of Food Composition and Analysis, vol. 31, no. 1, pp. 31–40, 2013. View at Publisher · View at Google Scholar · View at Scopus
  51. K. B. Pandey and S. I. Rizvi, “Plant polyphenols as dietary antioxidants in human health and disease,” Oxidative Medicine and Cellular Longevity, vol. 2, no. 5, pp. 270–278, 2009. View at Publisher · View at Google Scholar · View at Scopus
  52. S. I. Rizvi and K. B. Pandey, “Activation of the erythrocyte plasma membrane redox system by resveratrol: a possible mechanism for antioxidant properties,” Pharmacological Reports, vol. 62, no. 4, pp. 726–732, 2010. View at Publisher · View at Google Scholar
  53. R. K. Kesharwani, D. V. Singh, K. Misra, and S. I. Rizvi, “Plant polyphenols as electron donors for erythrocyte plasma membrane redox system: validation through in silico approach,” Organic and Medicinal Chemistry Letters, vol. 2, no. 1, p. 12, 2012. View at Publisher · View at Google Scholar
  54. B. C. B. Boaventura, P. F. Di Pietro, G. A. Klein et al., “Antioxidant potential of mate tea (Ilex paraguariensis) in type 2 diabetic mellitus and pre-diabetic individuals,” Journal of Functional Foods, vol. 5, no. 3, pp. 1057–1064, 2013. View at Publisher · View at Google Scholar · View at Scopus
  55. D. J. O’Byrne, S. Devaraj, S. M. Grundy, and I. Jialal, “Comparison of the antioxidant effects of Concord grape juice flavonoid and a-tocopherol on markers of oxidative stress in healthy adults,” American Journal of Clinical Nutrition, vol. 76, no. 6, pp. 1367–1374, 2002. View at Google Scholar
  56. A. Bub, B. Watzl, D. Heeb, G. Rechkemmer, and K. Briviba, “Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice,” European Journal of Nutrition, vol. 40, no. 3, pp. 113–120, 2001. View at Publisher · View at Google Scholar · View at Scopus
  57. S. B. Lotito and B. Frei, “Consumption of flavonoid-rich foods and increases plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?” Free Radical Biology and Medicine, vol. 41, no. 12, pp. 1727–1746, 2006. View at Publisher · View at Google Scholar · View at Scopus
  58. A. Day and D. Stansbie, “Cardioprotective effect of red wine may be mediated by urate,” Clinical Chemistry, vol. 41, no. 9, pp. 1319-1320, 1995. View at Google Scholar
  59. S. Cyboran, J. Oszmiański, and H. Kleszczyńska, “Interaction between plant polyphenols and the erythrocyte membrane,” Cellular and Molecular Biology Letters, vol. 17, no. 1, pp. 77–88, 2012. View at Publisher · View at Google Scholar · View at Scopus
  60. E. Birben, U. M. Sahiner, C. Sackesen, S. Erzurum, and O. Kalayci, “Oxidative stress and antioxidant defense,” World Allergy Organization Journal, vol. 5, no. 1, pp. 9–19, 2012. View at Publisher · View at Google Scholar · View at Scopus
  61. M. Anastasiadi, H. Pratsinis, D. Kletsas, A. L. Skaltsounis, and S. A. Haroutounian, “Bioactive non-coloured polyphenols content of grapes, wines and vinification by-products: evaluation of the antioxidant activities of their extracts,” Food Research International, vol. 43, no. 3, pp. 805–813, 2010. View at Publisher · View at Google Scholar · View at Scopus
  62. L. Xiang, L. Xiao, Y. Wang, H. Li, Z. Huang, and X. He, “Health benefits of wine: don’t expect resveratrol too much,” Food Chemistry, vol. 156, pp. 258–263, 2014. View at Publisher · View at Google Scholar · View at Scopus
  63. L. H. Long, M. V. Clement, and B. Halliwell, “Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (−)-epigallocatechin, (−)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media,” Biochemical and Biophysical Research Communications, vol. 273, no. 1, pp. 50–53, 2000. View at Publisher · View at Google Scholar · View at Scopus