Journal of Nutrition and Metabolism

Clinical Study

Efficacy of an Anthocyanin and Prebiotic Blend on Intestinal Environment in Obese Male and Female Subjects

Table 5

Bloating, abdominal pain, and gas severity in participants supplemented with the anthocyanin-prebiotic blend at baseline (day 0) and end of the study (day 57) ().


	Bloating severity ()	Abdominal pain severity ()	Gas severity ()
	Mean ± SD ()	Mean ± SD ()	Mean ± SD ()
	Median (interquartile range)	Median (interquartile range)	Median (interquartile range)
	Within-group value^a	Within-group value^a	Within-group value^a

Baseline (day 0)	2.11 ± 2.07 (46)	1.90 ± 1.83 (46)	2.40 ± 1.96 (46)
Baseline (day 0)	1.93 (2.77)	1.64 (2.74)	2.04 (2.39)

Change from baseline to week 1	−0.10 ± 1.00 (46)	0.09 ± 1.03 (46)	−0.02 ± 1.09 (46)
	−0.14 (1.20)	0 (1.04)	0.07 (0.93)
	0.125^c	0.914^b	0.843^b

Change from baseline to week 2	−0.12 ± 1.15 (46)	0.12 ± 1.15 (46)	−0.02 ± 1.16 (46)
	−0.14 (1.20)	0 (1.16)	−0.11 (1.09)
	0.054^c	0.972^b	0.462^b

Change from baseline to week 3	−0.35 ± 1.21 (46)	−0.18 ± 1.18 (46)	−0.16 ± 1.29 (46)
	−0.24 (0.98)	−0.07 (0.63)	−0.25 (1.21)
	0.005^c	0.050^b	0.340^b

Change from baseline to week 4	−0.61 ± 1.21 (46)	−0.44 ± 1.22 (46)	−0.36 ± 1.11 (46)
	−0.21 (1.21)	−0.14 (1.09)	−0.21 (1.09)
	<0.001^c	0.006^b	0.062^b

Change from baseline to week 5	−0.55 ± 1.34 (46)	−0.35 ± 1.35 (46)	−0.52 ± 1.31 (46)
	−0.14 (1.21)	−0.14 (0.92)	−0.29 (1.32)
	0.001^c	0.037^b	0.007^b

Change from baseline to week 6	−0.59 ± 1.25 (46)	−0.32 ± 1.30 (46)	−0.35 ± 1.38 (46)
	−0.14 (1.05)	−0.11 (0.85)	−0.36 (1.05)
	<0.001^c	0.031^b	0.056^b

Change from baseline to week 7	−0.52 ± 1.24 (46)	−0.33 ± 1.16 (46)	−0.34 ± 1.22 (46)
	−0.14 (1.11)	−0.04 (0.64)	−0.25 (0.71)
	0.002^c	0.014^b	0.043^b

Change from baseline to week 8	−0.42 ± 1.01 (46)	−0.28 ± 0.98 (46)	−0.26 ± 1.07 (46)
	−0.11 (1.18)	0 (0.70)	−0.21 (0.84)
	<0.001^c	0.014^b	0.035^b

: number; SD: standard deviation. ^aWithin-group comparisons were made using the paired Student’s t-test. ^bWithin-group comparisons were made using the signed-rank test. ^cSquare root transformation required to achieve normality. Probability values ≤0.05 are statistically significant.