Research Article
Zinc Deficiency and the Recurrence of Clostridium difficile Infection after Fecal Microbiota Transplant: A Retrospective Cohort Study
Table 3
Low zinc cohort characteristics.
| | | Not supplemented (n = 6) | Supplemented (n = 25) | Total (n = 31) | value | Test utilized |
| | Zinc | | | | | | | Serum zinc (mcg/ml) (SD) | 0.53 (0.08) | 0.52 (0.08) | 0.52 (0.08) | 0.907 | t-test | | Patient characteristics | | | | | | | Age, mean (SD) | 75.33 (12.03) | 66.72 (18.90) | 68.39 (17.94) | 0.299 | t-test | | Female gender, n (%) | 4 (66.67) | 12 (48.00) | 16 (51.61) | 0.654 | Fischer’s exact | | BMI, mean (SD) | 24.62 (5.34) | 27.78 (8.93) | 27.17 (8.37) | 0.417 | t-test | | Immunocompromised state, n (%) | 1 (16.67) | 7 (28.00) | 8 (25.81) | 1.000 | | | Charlson Comorbidity Index, mean (SD) | 2.00 (2.68) | 2.12 (2.13) | 2.10 (2.20) | 0.907 | | | IBD, n (%) | 1 (16.67) | 9 (36.00) | 10 (32.26) | 0.634 | Fischer’s exact | | Ulcerative colitis, n | 1 | 3 | 4 | | | | Crohn’s colitis, n | 0 | 2 | 2 | | | | Indeterminate colitis, n | 0 | 4 | 4 | | | | CDI history | | | | | | | # CDIs, mean (SD) | 4.83 (1.47) | 3.92 (1.41) | 4.10 (1.45) | 0.168 | t-test | | # CDIs 6 mo before FMT, mean (SD) | 3.17 (1.17) | 2.64 (1.08) | 2.74 (1.09) | 0.298 | t-test | | # CDI-hospitalizations, mean (SD) | 2.33 (2.42) | 0.96 (1.10) | 1.23 (1.50) | 0.228 | t-test | | # CDI-hospitalizations 6 mo before FMT, mean (SD) | 1.50 (1.64) | 0.68 (0.80) | 0.84 (1.04) | 0.283 | t-test |
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SD, standard deviation; BMI, body mass index; CDI, Clostridium difficile infection; IBD, inflammatory bowel disease; FMT, fecal microbiota transplant; mo, month.
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