Research Article
CNDP1, NOS3, and MnSOD Polymorphisms as Risk Factors for Diabetic Nephropathy among Type 2 Diabetic Patients in Malaysia
Table 4
Differences in the frequencies of allele distribution among the races.
| | SNP | Control | Case | | Malays | Chinese | Indians | value (χ2, df = 2) | Malays | Chinese | Indians | value (χ2, df = 2) |
| | CNDP1 | A = 161 | C = 31 | A = 140 | C = 50 | A = 187 | C = 41 | 0.028 | A = 213 | C = 49 | A = 161 | C = 49 | A = 94 | C = 40 | 0.042 | | rs2346061 | (83.9) | (16.1) | (73.7) | (26.3) | (82.0) | (18.0) | 7.1 | (81.3) | (18.7) | (76.7) | (23.3) | (70.1) | (29.9) | 6.32 | | CNDP1 | 5 = 45 | 6 = 147 | 5 = 43 | 6 = 147 | 5 = 118 | 6 = 154 | <0.05 | 5 = 29 | 6 = 233 | 5 = 27 | 6 = 209 | 5 = 52 | 6 = 120 | <0.001 | | D18S880 | (23.4) | (76.6) | (22.6) | (77.4) | (43.4) | (56.6) | 30.51 | (11.1) | (88.9) | (11.4) | (88.6) | (30.2) | (69.8) | 34.1 | | MnSOD | C = 166 | T = 26 | C = 167 | T = 23 | C = 232 | T = 38 | 0.920 | C = 203 | T = 59 | C = 153 | T = 47 | C = 131 | T = 41 | 0.942 | | rs4880 | (86.5) | (13.5) | (87.9) | (12.1) | (85.93) | (14.07) | 0.01 | (77.5) | (22.5) | (78.2) | (21.8) | (76.2) | (23.8) | 0.12 | | NOS3 | G = 166 | T = 26 | G = 166 | T = 26 | G = 236 | T = 38 | 0.842 | G = 202 | T = 57 | G = 165 | T = 51 | G = 131 | T = 41 | 0.878 | | rs1799983 | (86.5) | (13.5) | (86.5) | (13.5) | (85.5) | (14.5) | 0.04 | (78.0) | (22.0) | (76.4) | (23.6) | (76.2) | (23.8) | 0.26 |
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indicates the significant difference in allele distribution in the population. |
