Research Article

Fetal Growth Trajectories and Their Association with Maternal, Cord Blood, and 5-year Child Adipokines

Table 3

Estimated fetal weight trajectory class (slow, moderate, moderate-fast, very fast) and association with biochemical markers.

Weight trajectory classTotalSlow (4%)Moderate (63%)Moderate-fast (30%)Very fast (3%) value
nMedianIQRnMedianIQRnMedianIQRnMedianIQRnMedianIQR

Maternal samples at 28 weeks
 Leptin (pg/ml)53119641.7(14518.6, 34071.8)2315578.8(5815.9, 25562.5)33015711.1(8739.2, 26297.5)16216270.9(8876.2, 24449.0)1618891.8(13684.1, 31437.9)0.784
 Adiponectin (ng/ml)29124.1(16.6, 37.8)1222.7(16.1, 26.6)18526.1(15.1, 42.4)8727.9(15.9, 50.3)717.6(15.2, 31.1)0.315
 HOMA-IR5073.1(1.7, 5.1)213.21(1.8, 5.8)3162.8(1.6, 4.3)1553.1(1.8, 5.4)152.1(1.2, 5.1)0.567
 Insulin (IU)53117.2(9.0, 25.6)2216.5(9.5, 29.1)33414.3(8.9, 22.1)16015.3(8.8, 26.5)159.8(6.4, 26.5)0.302

Cord blood samples
 Cord leptin (ng/ml)10828479.9(16482.7, 47203.2)311765.3(10556.3, 22808.5)7519633.1(12751.4, 35212.8)2722162.9(8945.7, 42044.6)319288.0(12621.2, 37457.4)0.212
 Cord adiponectin (ng/ml)10880.2(22.0, 915.1)396.2(37.7, 192.4)75141.3(62.5, 327.5)27139.4(46.7, 227.7)357.9(43.7, 78.5)0.700

5-year child samples
 Leptin (ng/ml)8377.0(19.7, 151.6)1443.1-54184.6(87.8, 418.1)24242.6(74.8, 465.9)430.2(13.1 -0.880
 Adiponectin (ng/ml)8317.1(7.5, 21, 7)10.2-5411.4(4.2, 17.9)2413.9(5.6, 18.5)411.61.6 -0.913

Kruskal–Wallis.