Fetal Growth Trajectories and Their Association with Maternal, Cord Blood, and 5-year Child Adipokines

Table 4

Abdominal circumference trajectory (slower or fast) associated with biochemical markers.

Abdominal circumference trajectory class	Total			Slower (29%)			Fast (71%)			value
	n	Median	IQR	n	Median	IQR	n	Median	IQR
Maternal blood at 28 weeks
Leptin (ng/ml)	524	16970.1	(9705.2, 26962.5)	129	25616.4	(11656.0, 35341.0)	395	14753.8	(8565.4, 24308.1)	<0.001
Adiponectin (ng/ml)	290	25.6	(15.4, 41.8)	91	22.4	(13.6, 35.9)	199	27.6	(17.6, 46.3)	0.027
HOMA-IR	503	2.9	(1.5, 4.7)	129	3.2	(1.6, 5.2)	374	2.8	(1.5, 4.8)	0.258
Insulin (IU)	526	14.6	(8.0, 23.0)	134	15.7	(8.7, 26.0)	392	14.5	(8.0, 23.8)	0.258
Cord blood samples
Cord leptin (ng/ml)	105	18567.1	(14477.7, 41437.6)	22	21072.4	(11795, 35439.4)	83	19503.9	(12015.7, 37501.2)	0.892
Cord adiponectin (ng/ml)	105	104.1	(22.0, 915.1)	22	144.0	(53.5, 270.4)	83	131.0	(59.1, 131.0)	0.877
5-year child samples
Leptin (ng/ml)	83	77.0	(19.7, 151.6)	24	205.1	(70.8, 443.0)	59	169.8	337.3	0.791
Adiponectin (ng/ml)	83	17.1	(7.5, 21.7)	24	13.6	(0.8–18.1)	59	10.2	12.8	0.931

HOMA-IR: homeostatic model assessment of insulin resistance, Mann–Whitney.