Insulin Resistance Indexes as Biomarkers of Lifetime Cardiovascular Risk among Adults from Peru

Table 4

Diagnostic accuracy of TG/HDL-C and TyG in predicting lifetime cardiovascular risk and their optimal cutoff values.

Predictors	Overall	Men	Women
	Value (CI 95%)	Value (CI 95%)	Value (CI 95%)
TG/HDL-C
Optimal cutoff^a	2.64	3.90	2.64
AUC	0.77 (0.71–0.83)	0.80 (0.70–0.90)	0.74 (0.65–0.83)
Sensitivity	0.86 (0.76–0.94)	0.66 (0.49–0.80)	0.86 (0.68–0.96)
Specificity	0.60 (0.54–0.67)	0.87 (0.74–0.95)	0.60 (0.52–0.67)
PPV	0.39 (0.33–0.60)	0.81 (0.64–0.90)	0.26 (0.20–0.58)
NPV	0.94 (0.88–0.95)	0.75 (0.60–0.90)	0.96 (0.90–0.97)
TyG
Optimal cutoff^a	9.04	8.95	9.04
AUC	0.80 (0.74–0.86)	0.79 (0.69–0.89)	0.80 (0.72–0.88)
Sensitivity	0.64 (0.51–0.76)	0.68 (0.51–0.82)	0.66 (0.46–0.82)
Specificity	0.83 (0.77–0.88)	0.80 (0.66–0.91)	0.82 (0.76–0.88)
PPV	0.53 (0.44–0.66)	0.74 (0.58–0.86)	0.38 (0.29–0.60)
NPV	0.88 (0.82–0.92)	0.76 (0.60–0.88)	0.94 (0.87–0.96)

AUC, area under the curve; TG/HDL-C, triglycerides to HDL-cholesterol ratio; TyG, triglyceride glucose index; PPV, positive predictive value; NPV, negative predictive value.