glutamin supplement specif group critic ill patient result favour clinic outcom enhancement citrullin arginin synthesi glutamin could serv potenti mechan howev while receiv optim enter nutrit uptak enter metabol glutamin critic ill patient remain unknown therefor investig effect therapeut relev dose lglutamin synthesi lcitrullin subsequ larginin group ten versus ten critic ill patient receiv full enter nutrit isocalor isonitrogen enter nutrit includ 05 lalanyllglutamin were studi use stabl isotop crossov design use intraven enter tracer enabl splanchnic extract calcul endogen rate appear glutamin citrullin arginin differ control versus alanylglutamin glutamin 48 48 citrullin 33 versus 45 arginin 45 versus 42 turnov from glutamin citrullin arginin higher glutamineadminist patient critic ill nonsept patient receiv adequ nutrit relev dose glutamin extra citrullin arginin synthesi glutamin increas this suggest arginin synthesi enhanc need addit dose glutamin when popul adequ fed this trial regist ntr2285

Mechteld A. R. Vermeulen

Saskia J. H. Brinkmann

Nikki Buijs

Albertus Beishuizen

Pierre M. Bet

Alexander P. J. Houdijk

Johannes B. van Goudoever

Paul A. M. van Leeuwen

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

manufactur dark chocol other cocoabas product complex multistag process begin spontan cocoa bean ferment driven postharvest period differ microorgan deriv from environ cocobiota defin associ microbi speci involv cocoa bean ferment may have consider impact medicin properti cocoa product via various primari secondari metabolit whose presenc dark chocol other cocoaderiv product has taken consider when analyz medicin effect cocoa metabolit acet acid lactic acid bacteria two major cocobiota member recent shown have consider antifung cholesterollow activ promot format short chain fatti acid mannitol import prebiot capabl modifi gut microbiota penicillium citrinum major type fungi identifi ferment cocoa bean produc thermost alkaloid penicitrinin well lovastatin compound antineoplast cholesterollow abil respect moreov recent result suggest bacteri fungal metabolit produc cocobiota have signific antiinfect potenti therefor various metabolit produc cocobiota can mimic some medicin effect dark chocol other cocoaderiv product previous attribut cocoa flavonoid methylxanthin need thorough investig vitro vivo system

Ivan M. Petyaev

Yuriy K. Bashmakov

Cocobiota: Implications for Human Health

the effect feruloyl arabinoxylan mono oligosaccharid faxmo mammalian glucosidas glucos transport investig use human caco2 cell rat intestin aceton powder xenopus laevi oocyt the isol faxmo from wheat aleuron corn bran were identifi have degre polymer 4 1 respect hplcms both faxmo extract were effect inhibitor sucras maltas function glucosidas the ic50 faxmo extract caco2 cell rat intestin glucosidas 103165 2665 respect similar glucos uptak caco2 cell inhibit 40 the inhibitori effect faxmo depend ferul acid content 095 sodium independ glucos transport 2 glut2 activ complet inhibit faxmo oocyt inject express glut2 our result suggest ferul acid feruloyl arabinoxylan mono oligosaccharid have potenti use diabet manag

Lovemore Nkhata Malunga

Peter Eck

Trust Beta

Inhibition of Intestinal &#x3b1;-Glucosidase and Glucose Absorption by Feruloylated Arabinoxylan Mono- and Oligosaccharides from Corn Bran and Wheat Aleurone

iodin requir product thyroid hormon essenti growth develop brain all form iodin defici affect mental develop child our studi aim assess impact intellectu develop moroccan schoolchildren evalu effect consumpt fortifi milk reduc doubleblind control trial conduct schoolchildren children were divid two group receiv fortifi milk 30 cover rdi iodin nonfortifi milk 9 month urinari iodin analyz use sandellkolthoff reaction dynam cognit test use raven standard progress matric assess learn potenti perform baselin end line anthropometr assess done onli baselin the studi includ schoolchildren who were sever iodin defici the preval malnutrit high both group studi found improv iodin status cognit abil among moroccan schoolchildren our studi show consumpt fortifi milk led clear improv iodin status also appear have favor effect cognit abil moroccan schoolchildren rural mountain region

Fatima Ezzahra Zahrou

Mehdi Azlaf

Imane El Menchawy

Mohamed El Mzibri

Khalid El Kari

Asmaa El Hamdouchi

Fatima-Zahra Mouzouni

Amina Barkat

Hassan Aguenaou

Fortified Iodine Milk Improves Iodine Status and Cognitive Abilities in Schoolchildren Aged 7&#x2013;9 Years Living in a Rural Mountainous Area of Morocco

some botan have been report possess antioxid activ act scaveng free radic render usag herbal medicin here describ potenti use sal standard blend compris three extract from schisandra chinensi artemisia capillari aloe barbadensi mitig chemic induc acut liver toxic acetaminophen carbon tetrachlorid induc acut liver toxic model mice were util hepat function test from serum collect t24 hepat glutathion superoxid dismutas from liver homogen were evalu histopatholog analysi merit blend 3 standard extract were also confirm statist signific dosecorrel inhibit serum alt rang from 525 346 apap 463 299 ccl 4 model were observ sal administ dose 400250 moreov sal result 606 802 reduct serum ast bile acid respect the composit replenish deplet hepat glutathion associ increas hepat superoxid dismutas unexpect synergist protect from liver damag also observ therefor composit sal could potenti util effect hepaticdetoxif agent protect from liver damag

Mesfin Yimam

Ping Jiao

Breanna Moore

Mei Hong

Sabrina Cleveland

Min Chu

Qi Jia

Young-Chul Lee

Hyun-Jin Kim

Jeong-Bum Nam

Mi-Ran Kim

Eu-Jin Hyun

Gayoung Jung

Seon Gil Do

Hepatoprotective Activity of Herbal Composition SAL, a Standardize Blend Comprised of Schisandra chinensis, Artemisia capillaris, and Aloe barbadensis

absorption metabol excret 34dhpeaeda oleuropein hydroxytyrosol isol from oliv fruit were newli evalu after oral intraven administr free move rat cannul portal vein jugular vein bile duct oralli administ 34dhpeaeda import bioactiv compound oliv pomac readili absorb metabol hydroxytyrosol homovanil acid homovanillyl alcohol shown dosenorm 4 area under curv dose valu 277 45 42 min mol respect portal plasma after oral administr the parent compound 34dhpeaeda observ portal plasma urin bile after oral intraven administr addition hydroxytyrosol homovanil acid homovanillyl alcohol portal plasma after oral administr hydroxytyrosol show 511 228 71 min mol dose respect when oleuropein polar glucosid inject oral oleuropein portal plasma show 09 min mol dose howev homovanil acid detect from oleuropein onli small amount portal plasma moreov bioavail hydroxytyrosol oleuropein 4 hour 131 05 respect becaus amount 34dhpeaeda oliv fruit about 23 time greater than hydroxytyrosol metabolit 34dhpeaeda influenc biolog activ

Shunsuke Kano

Haruna Komada

Lina Yonekura

Akihiko Sato

Hisashi Nishiwaki

Hirotoshi Tamura

Absorption, Metabolism, and Excretion by Freely Moving Rats of 3,4-DHPEA-EDA and Related Polyphenols from Olive Fruits (Olea europaea)

background 8prenylnaringenin 8pn phytoestrogen highest affin estrogen receptor which requir maintain bmd the osteoprotect properti 8pn have been demonstr previous tibia use rat osteopenia model perform first investig 8pn wholebodi vertic vibrat wbvv studi design ovariectomi perform 52 64 spraguedawley rat five week after ovariectomi one group receiv daili inject 8pn 177 10 week second group treat both 8pn wbvv twice day 15 min 35 amplitud 047 other group receiv either onli wbvv treatment method the rat were sacrif 15 week after ovariectomi lumbar vertebra femora were remov biomechan morpholog assess result 8pn cancersaf dose did caus fundament improv osteoporot bone treatment 8pn caus slight increas uterin wet weight combin therapi use wbvv 8pn show signific improv bone structur biomechan properti conclus cannot confirm osteoprotect effect 8pn cancersaf dose primari affect osteoporot bone higher concentr 8pn advis safeti reason adjunctiv therapi wbvv demonstr convinc effect bone

Daniel B. Hoffmann

Markus H. Griesel

Bastian Brockhusen

Mohammad Tezval

Marina Komrakova

Bjoern Menger

Marco Wassmann

Klaus Michael Stuermer

Stephan Sehmisch

Effects of 8-Prenylnaringenin and Whole-Body Vibration Therapy on a Rat Model of Osteopenia

breakfast higher protein lead greater reduct hunger compar breakfast higher carbohydr howev few studi have examin impact higher protein breakfast differ protein sourc our object determin protein sourc anim protein versus plant protein influenc postprandi metabol respons particip consum high protein breakfast 30 energi from protein normal weight overweight women age 1836 were recruit particip particip complet two visit random crossov design one week between visit subject had 15 minut consum each breakfast blood glucos appetit were assess baselin 15 30 45 60 120 minut postprandi particip kept 24hour dietari record durat each test day differ found between particip breakfast postprandi appetit respons had signific lower glucos respons 30 minut compar 116 127 4 versus 112 4 slower return baselin there differ daili energi intak between breakfast these data suggest protein sourc may influenc postprandi glucos respons without signific impact appetit respons breakfast consum

Christina M. Crowder

Brianna L. Neumann

Jamie I. Baum

Breakfast Protein Source Does Not Influence Postprandial Appetite Response and Food Intake in Normal Weight and Overweight Young Women

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