Research Article

Magnetic Fluid Hyperthermia of Rodent Tumors Using Manganese Perovskite Nanoparticles

Table 3

Lewis lung carcinoma growth and metastasis value after treatment of primary tumor with MF combined with AMF.

Animal groupsChange in the volume of primary tumor (on the 15th day after the treatment)Number of metastases in lungs per mice

Nontreated tumor-bearing mice, Increase by 20-fold24 ± 2.3
Nanohyperthermia of primary tumor, Increase by 5-fold
(complete regression of primary tumor was determined in 57% of mice. Tumors have regressed mostly through necrosis and following rejection of tumor mass)
8 ± 0.8 
(lung metastases were not determined in 43% of mice among all mice which have been treated)

: number of mice.