Table of Contents
Journal of Nanoparticles
Volume 2016, Article ID 6898926, 9 pages
http://dx.doi.org/10.1155/2016/6898926
Research Article

Vitis vinifera Assisted Silver Nanoparticles with Antibacterial and Antiproliferative Activity against Ehrlich Ascites Carcinoma Cells

1Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi 6205, Bangladesh
2Department of Food Science and Technology, Pukyong National University, 45 Yongso-Ro, Nam-Gu, Busan 608-737, Republic of Korea

Received 24 May 2016; Accepted 27 July 2016

Academic Editor: Xiangwu Zhang

Copyright © 2016 A. K. M. Asaduzzaman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Vitis vinifera extract assisted silver nanoparticles (AgNPs) were biosynthesized that was confirmed primarily by color change and a sharp plasmon absorption band was found at 449 nm. Biosynthesized AgNPs shape was spherical and the particle size of 17 nm in average was confirmed by transmission electron microscopy (TEM) images. Functional groups of AgNPs were identified by Fourier transform infrared spectroscopy (FTIR). Streptococcus aureus was the most sensitive bacteria towards the assisted V. vinifera AgNPs as their growth was 90% inhibited at 100 μg/mL concentration. That was also confirmed by the zone of inhibition study. Up to 96 h, no biofilm was observed for K. pneumoniae at 40 μg/mL of AgNPs. Although AgNPs showed a mild toxicity against brine shrimp nauplii, it showed a remarkable level of antiproliferative activity against Ehrlich ascites carcinoma (EAC) cells.