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Journal of Nanotechnology
Volume 2011, Article ID 617196, 9 pages
http://dx.doi.org/10.1155/2011/617196
Research Article

Intermediate Frequency AC Signal Analysis for Bionanosensor

1Department of Electrical and Computer Engineering, University of New Haven, 300 Boston Post Road, West Haven, CT 06516, USA
2Department of Biology and Environmental Science, University of New Haven, 300 Boston Post Road, West Haven, CT 06516, USA
3Department of Physics, University of New Haven, 300 Boston Post Road, West Haven, CT 06516, USA
4Department of Biomedical Engineering, University of Bridgeport, 126 Park Avenue, Bridgeport, CT 06604, USA
5Department of Mechanical Engineering, University of Bridgeport, 126 Park Avenue, Bridgeport, CT 06604, USA

Received 11 May 2011; Revised 16 July 2011; Accepted 11 August 2011

Academic Editor: Andrei Kolmakov

Copyright © 2011 Vishal Desai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nanobiosensors are devices which incorporate nanomaterials to detect miniscule quantities of biological and chemical agents. The authors have already developed a novel bionanosensor (BNS) for quick, efficient, and precise detection of bacterial pathogens using the principles of CNT-DNA interaction and DNA hybridization. The detection ability of the (BNS) was observed to be independent of the device resistance. Two new methods (low-pass filter (LPF) and curve fitting (CF)) were developed for better analysis of the BNS. These methods successfully model the BNS. Evidence is provided to elucidate the success of the model, which can explain the DNA hybridization on the sensor surface. These models successfully demonstrated the detection of DNA hybridization versus nonhybridization. Thus, the models can not only help in better and efficient design and operation of the BNS, but can also be used to analyze other similar nanoscale devices.