Preparation of Lipid Nanoemulsions Incorporating Curcumin for Cancer Therapy

Table 2

IC₅₀ values (μM) of curcumin and curcumin-loaded nanoemulsion on B16F10, K562, Molt4, U937, and HL-60 cell lines.

Treatment	IC50 (μM)
	B16F10	K562	Molt4	U937	HL-60
Curcumin	3.5±0.5	38.7±2.0	14.4±2.3	30.1±0.9	15.7±1.6
Curcumin-loaded nanoemulsion	22.2±0.6 *	53.7±0.23	30.3±4.4	35.8±1.7	23.5±1.1
Nanoemulsion control	>67.9	>67.9	>67.9	>67.9	>67.9

Each value denotes the mean ± SE of three independent experiments (𝑛=3).
*Significantly different from the curcumin (𝑃<0.05).