Table 1: Different polymeric nanoparticles used as nanocarriers.

Polymeric nanocarrierStructureCharacteristicsTechnology applied in biomedicineCompanyReference

Nanoparticles (polymer-substance conjugate)Substance of interest is conjugated to the side chain of a linear polymer with a linkerWater-soluble, nontoxic, biodegradable.
Surface modification (pegylation) 

Selective accumulation and retention in tumor tissue when used as drug carrier 

Specific targeting of certain cells through receptor-mediated targeting with a ligand
Polymeric nanoparticles engineered to carry antitumor drugs across blood-brain barrier 

Biodegradable polymeric nanoparticles for drug delivery 

Polybutylcyanoacrylate nanoparticles coated with drugs and then a surfactant which go across blood-brain barrier
Advectus Life Sciences Inc.

Alnis Biosciences, Inc.

NanoPharm AG
[9, 27]

MicellesAssembly of amphiphilic block copolymers forming a micelle with a hydrophobic shellSuitable carriers for water-insoluble drugs 

Biocompatible, self-assembling, and biodegradable 

Ease of functional modification can become targeted
Glucose level monitoring in diabetes mellitus

Encapsulation of insulin for treatment of diabetes 

Cell membrane and intracellular labeling 
Encapsulation of drugs, protein DNA 
Magnetic cores surrounded by a polymeric layer coated with antibodies for capturing cells
NanoCarrier Co., Ltd.


DendrimersHyperbranched synthetic polymer with regular pattern and repeated unitsBiodistribution pharmacokinetics can be controlled

High structural and chemical homogeneity 

Easily functionalized 

Allows high ligand and drug density 

Controlled degradation 

Water soluble dendrimer based contrast agents for computed tomography 

Delivery of chemotherapeutic drugs
Starpharma[21, 22]