TY - JOUR A2 - Baguley, Bruce AU - Woodall, Charles E. AU - Duvall, Ryan AU - Scoggins, Charles R. AU - McMasters, Kelly M. AU - Martin, Robert C. G. PY - 2008 DA - 2009/02/05 TI - Esophageal Carcinoma Histology Affects Perioperative Morbidity Following Open Esophagogastrectomy SP - 389394 VL - 2008 AB - Background. Esophagectomy for esophageal cancer is being practiced routinely with favorable results at many centers. We sought to determine if tumor histology is a powerful surrogate marker for perioperative morbidity. Methods. Seventy three consecutive patients managed operatively were reviewed from our prospectively maintained database. Results. Adenocarcinoma (AC) was present in 52 (71%) and squamous cell (SCC) in 21 (29%). The use of neoadjuvant therapy was similar for the AC (34.62%) and SCC (42.86%) groups. The SCC group had a higher incidence of prior pulmonary disease than the AC group (23.8% versus 5.8%, resp.; P=.03). SCC patients were more likely to have a prolonged ICU stay than AC patients (P=.004) despite similar complication rates, EBL, and prognostic nutritional index. The SCC group did, however, experience higher grades of complications (P=.0053). Conclusions. Presence of SCC was the single best predictor of prolonged ICU stay and more severe complications as defined by this study. Only a past history of pulmonary disease was different between the two histologic subgroups. SN - 1687-8450 UR - https://doi.org/10.1155/2008/389394 DO - 10.1155/2008/389394 JF - Journal of Oncology PB - Hindawi Publishing Corporation KW - ER -