TY - JOUR
A2 - Baguley, Bruce
AU - Woodall, Charles E.
AU - Duvall, Ryan
AU - Scoggins, Charles R.
AU - McMasters, Kelly M.
AU - Martin, Robert C. G.
PY - 2008
DA - 2009/02/05
TI - Esophageal Carcinoma Histology Affects Perioperative Morbidity Following Open Esophagogastrectomy
SP - 389394
VL - 2008
AB - Background. Esophagectomy for esophageal cancer is being practiced routinely with favorable results at many centers. We sought to determine if tumor histology is a powerful surrogate marker for perioperative morbidity. Methods. Seventy three consecutive patients managed operatively were reviewed from our prospectively maintained database. Results. Adenocarcinoma (AC) was present in 52 (71%) and squamous cell (SCC) in 21 (29%). The use of neoadjuvant therapy was similar for the AC (34.62%) and SCC (42.86%) groups. The SCC group had a higher incidence of prior pulmonary disease than the AC group (23.8% versus 5.8%, resp.; P=.03). SCC patients were more likely to have a prolonged ICU stay than AC patients (P=.004) despite similar complication rates, EBL, and prognostic nutritional index. The SCC group did, however, experience higher grades of complications (P=.0053). Conclusions. Presence of SCC was the single best predictor of prolonged ICU stay and more severe complications as defined by this study. Only a past history of pulmonary disease was different between the two histologic subgroups.
SN - 1687-8450
UR - https://doi.org/10.1155/2008/389394
DO - 10.1155/2008/389394
JF - Journal of Oncology
PB - Hindawi Publishing Corporation
KW -
ER -