Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival: Results from a Single Institutional Study

Table 2

Patient, tumor, and treatment characteristics.

Parameters	Preoperative EBRT group (𝑛=19)	Postoperative EBRT group (𝑛=12)	P value
Gender
Female	12 (63%)	8 (67%)	1.00
Male	7 (37%)	4 (33%)
Age at presentation
≤50 years	8 (42%)	2 (17%)	.24
>50 years	11 (58%)	10 (83%)
AJCC stage
I	5 (26%)	5 (42%)	.24
III	12 (63%)	3 (25%)
IV	2 (11%)	2 (17%)
Grade
1	3 (16%)	3 (25%)	.66
2	4 (21%)	2 (17%)
3	12 (63%)	5 (42%)
Tumor size
≤10 cm	7 (37%)	9 (75%)	.07
>10 cm	12 (63%)	3 (25%)
Lesion presentation
Primary	17 (89%)	7 (58%)	.08
Recurrent	2 (11%)	5 (42%)
Histology
Leiomyosarcoma	9 (47%)	6 (50%)	.72
Liposarcoma	7 (37%)	3 (25%)
Other	3 (16%)	3 (25%)
Extent resection
STR	4 (21%)	1 (8%)	.62
GTR	15 (79%)	11 (92%)
Organs removed
No	9 (47%)	3 (25%)	.27
Yes	10 (53%)	9 (75%)
Chemo
No	16 (84%)	9 (75%)	.65
Yes	3 (16%)	3 (25%)
IORT
No	6 (32%)	9 (75%)	.03
Yes (1 pt each arm had 2 fields)	13 (68%)	3 (25%)
Radiotherapy dose
EBRT median (range)	59.4 Gy (36.8–63.4 Gy)	59.4 Gy (54–68.4)	.79
IORT median (range)	11 Gy (10–12 Gy)	11 Gy (10–12 Gy)
IMRT
No	17 (89%)	4 (33%)	.002
Yes	2 (11%)	8 (67%)
Time to complete EBRT Median (range)	45 days (17–90 days)	44 days (41–55 days)	.76
Length of F/U Median (range)	22 months (0.6–56.5 months)	13.05 months (1.4–66.4 months)	.55

EBRT = external beam radiation therapy; STR = subtotal resection; GTR = gross total resection; IORT = intraoperative radiation therapy; IMRT = intensity modulated radiation therapy; F/U = follow-up.