Clinical Applications of FDG PET and PET/CT in Head and Neck Cancer

Table 1

Studies comparing accuracy of FDG PET and PET/CT with CT and MRI for detection of lymph nodes metastases.

Author year	Number of patients	Tumor Subtypes	Results	Notes
Beak et al. [2], 2009	15	Periorbital	PET/CT accuracy (98%) > CT 84%	- CT: 16 slice. - PET modified Tx in 39%.
Roh et al. [3], 2007	167	HNSCC	PET or PET/CT accuracy (92%-93%) > CT/MR 85%-86%	- PET/CT significantly better for detection of primary tumor
Gordin et al. [4], 2007	35	Nasopharyngeal	PET/CT accuracy 91% > PET 80% > CT 60%	- Retrospective - PET/CT modified TX in 57%
Kim et al. [5], 2007	32	Oropharyngeal	PET sensitivity 21% higher than CT/MR (𝑃<.05)	- PET/CT significantly better for detection of primary tumor
Dammann et al. [6], 2005	79	Oral cavity and oropharynx	PET accuracy 96% > MRI 94% > CT 92%	- Nonhyprid PET/CT used
Ng et al. [7], 2005	124	Oral cavity SCC	PET accuracy 98.4% > CT/MR 87.1%	- Prospective