MicroRNAs as New Players for Diagnosis, Prognosis, and Therapeutic Targets in Breast Cancer

Table 1

List of miRNAs and their target gene involved in human breast cancer.

MicroRNA	Targets	Aberrant expression and roles	References
MiR-21	BCL2, TPM1, PDCD4, PTEN	Overexpressed and play oncogenic role	[14–17]
MiR-10b	Homeobox D10	Down modulated, but associated with metastatic potential	[20]
MiR-27a	ZBTB10	Oncogenic role in breast cancer cells	[21]
MiR-206	ER𝛼	Overexpressed	[22, 23]
MiR-17-5p	AIB1	Oncosuppressor in breast cell lines	[24]
MiR-125a, miR-125b	ERBB2, ERBB3	Down modulated and act as oncosuppressor	[9, 25]
Let-7	RAS, HMGA2	Down modulated and reduced in BT-ICs	[26]
MiR-205	HER3	Down modulated	[27]