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Journal of Oncology
Volume 2009, Article ID 310132, 6 pages
Review Article

Eosinophils and Oral Squamous Cell Carcinoma: A Short Review

Laboratory of Oral and Maxillofacial Pathology, Division of Stomatology and Oral Surgery, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland

Received 24 April 2009; Revised 7 August 2009; Accepted 13 September 2009

Academic Editor: James L. Mulshine

Copyright © 2009 C. P. Martinelli-Kläy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The eosinophil cell has been related as a prognostic indicator for cancers. However, its exact function in tumour behaviour is still not clearly defined. In the oral cavity the presence of eosinophils can be a favourable prognostic indicator as well as it may be associated with a poor prognosis. In this short review, we briefly summarize the role of the eosinophils in the general context of immunoregulation and its relation to oral squamous cell carcinoma.