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Journal of Oncology
Volume 2009, Article ID 579407, 3 pages
Case Report

Rapid Fatal Outcome from Pulmonary Arteries Compression in Transitional Cell Carcinoma

Department of Medical Oncology, University Hospital of Larissa, Larissa 41110, Greece

Received 13 July 2009; Accepted 1 October 2009

Academic Editor: Thomas R. Chauncey

Copyright © 2009 Ioannis A. Voutsadakis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Transitional cell carcinoma of the urinary bladder is a malignancy that metastasizes frequently to lymph nodes including the mediastinal lymph nodes. This occurrence may produce symptoms due to compression of adjacent structures such as the superior vena cava syndrome or dysphagia from esophageal compression. We report the case of a 59-year-old man with metastatic transitional cell carcinoma for whom mediastinal lymphadenopathy led to pulmonary artery compression and a rapidly fatal outcome. This rare occurrence has to be distinguished from pulmonary embolism, a much more frequent event in cancer patients, in order that proper and prompt treatment be initiated.