Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma
Table 1
Demographic data for patient with multiple recurrences of well-differentiated thyroid carcinoma.
N
31
Age, median (range), years
43 (16–83)
Sex, M:F
11:20
Histologic type
Papillary
19
Follicular
4
Mixed
3
Tall cell
5
Tumour size, median (range), cm
3.3 (0.5–5.5)
Multifocal disease
21
Extrathyroidal extension
18
Lymphatic invasion
18
Vascular invasion
3
Distant metastasis
6
AJCC stage
I
4
II
8
III
11
IV
8
MACIS, median (range)
6.03 (3.25–11.02)
Extent of initial surgery
Subtotal thyroidectomy
12
Total thyroidectomy
19
Neck dissection
15
Lodine 131 therapy
27
External beam radiation therapy
10
Site of recurrence
Local
6
Regional
15
Distant
6
Unspecified
4
Outcome
Alive, no evidence of disease
9
Alive with disease
12
Dead of disease
10
Dead, no evidence of disease
0
Follow–up, median (range), years
12.6 (9months35.5years)
AJCCAmerican JOINT Committee on Cancer. Data is for the number of patients in each category. central +/- lateral neck dissection. Unspecified recurrence-elevated thyroglobulin levels in the presence of a negative clinical exam and failure of localization with imaging modalities (i.e., ultrasonography, I131 scanning, CT and MRI).
