Angiogenesis: From Chronic Liver Inflammation to Hepatocellular Carcinoma

Figure 5

Hepatic angiogenesis: during liver regeneration, newly formed sinusoids have normal architecture consistent with their physiological roles. In contrast, pathological hepatic angiogenesis leads to the capillarization of hepatic sinusoids with the result that the structure of sinusoids becomes distorted and characteristic endothelial fenestrations are lost.