Review Article
Targeted Therapies in Epithelial Ovarian Cancer
Table 3
Major risks factors potentially associated with bevacizumab-induced arterial thrombo-embolism and gastrointestinal perforation.
| 1- Arterial Thromboembolic Events (ATEs) [26] | –Age 65 years | –Prior history of ATE | 2- Gastrointestinal Perforation [27, 28] | –Multiple prior chemotherapy regimens (heavily pretreated patients) | –Large intraabdominal tumor burden | –Neoplastic bowel involvement | –Clinical evidence of partial obstruction |
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