Mesenchymal Migration as a Therapeutic Target in Glioblastoma

Figure 1

Glioblastoma cells follow the tracks created by other cells in 3D collagen gels. U87-MG glioblastoma cells were seeded into collagen type I gels for 24 hours, and then 24-hour time-lapse imaging was performed to track cell migration. Arrows (↑) indicate a “leading” cell and a “follower” cell, and arrows heads (∧) indicate the single path that they both follow in the collagen gel.