Review Article

Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

Figure 1

Images of twenty-four CTC candidates identified by the CellTracks Analyzer II. The images show an overlay of DAPI purple and CK-PE green. No staining was observed in the CD45 APC and FITC channel at the position of the CTC candidates. Six operators trained to review CellSearch CTC data classified objects 1–10, 13–17 as CTC, and discard objects 20–24 as CTC. 1 of 6 operators classified object 11 as a CTC and 5 of 6 operators classified object 12, 18, and 19 as a CTC.
617421.fig.001