Research Article
Role of Angiopoietin-2 in Regulating Growth and Vascularity of Astrocytomas
Table 1
Effect of Ang2 on subcutaneous xenograft models of GBM.
| | U87MG:Ctl | U87MG:Ang2 | U373:Ctl | U373MG:Ang2 | | = 8 | = 15 | = 15 | = 15 |
| Final Tumor Size (cm3) | 2.01 | 5.7 * | 3.18 | 5.96 | (SEM 0.3) | (SEM 0.4) | (SEM 0.3) | (SEM 0.5) | | | | |
| Proliferation Index | 0.23 | 0.75* | 0.042 | 0.28 | | | | |
| MVD (vessels/HPF) mean of 10 counts | 2.12 | 9.5* | 3 | 3.9* | (SEM 0.1) | (SEM 0.1) | (SEM 0.1) | (SEM 0.2) | | | | |
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SEM = Standard Error of Mean ndicates statistical significance.
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