Journal of Oncology / 2010 / Article / Fig 1

Research Article

Significant Growth Inhibition of Canine Mammary Carcinoma Xenografts following Treatment with Oncolytic Vaccinia Virus GLV-1h68

Figure 1

Cytotoxicity (a) and replication (b) of the GLV-1h68 virus in canine mammary MTH52c cells. (a) Viability of MTH52c cells after GLV-1h68 infection using MOIs of 0.1 and 1 was monitored over 96 hours. The amount of viable cells after infection with GLV-1h68 was measured in triplicate. Values are shown as percentages of respective uninfected controls. (b) Viral titer analysis in MTH52c cell culture after infection with GLV-1h68 at an MOI of 0.1. Cells and supernatant of virally treated cells were collected at various times post infection. Viral titers were determined as pfu per well in triplicate by plaque assay in CV-1 cell monolayers. Average plus standard deviations plotted.

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