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Journal of Oncology
Volume 2010, Article ID 781621, 10 pages
Review Article

Current Status and Future Prospects of Proton MR Spectroscopy of the Breast with a 1.5T MR Unit

1Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba 296-8602, Japan
2Siemens Japan K.K. Healthcare Sector, 3-20-14 Higashi-Gotanda, Shinagawa-ku, Tokyo 141-8644, Japan

Received 30 April 2010; Accepted 1 September 2010

Academic Editor: Massimo Aglietta

Copyright © 2010 Mitsuhiro Tozaki and Katsuya Maruyama. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Proton MR spectroscopy of the mammary gland area is used to be considered in the realm of basic research, but as a result of the advances in MR techniques, it is now being performed in ordinary clinical practice. It is particularly noteworthy that useful clinical data are now being accumulated with 1.5T MR units, which are the standard units. We think that, at this point, it is very important to systematically review the techniques, clinical applications, and future prospects of proton MR spectroscopy. We have performed proton MR spectroscopy with a 1.5T MR unit in over 3000 cases at our hospital. In this paper, we will comment on the current status of proton MR spectroscopy of the breast, primarily in regard to differentiation between benign and malignant lesions and prediction of the efficacy of chemotherapy while describing the data obtained at our hospital.