Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers

Figure 4

Chemosensitivity to paclitaxel induced by miR-200c expression. (a) Clonogenic assay in Hey cells either mock transfected, transiently transfected with a negative control, or miR-200c mimic and treated with 0–5 nM paclitaxel. The total area (b) and number of colonies (c) at 5 nM paclitaxel are quantified. Asterisks indicate statistically significant difference (P $<$ .05, Student’s $t$-test) versus negative controls.