Current and Future Trends in Magnetic Resonance Imaging Assessments of the Response of Breast Tumors to Neoadjuvant Chemotherapy

Figure 4

Biomedical informatics system architecture to support cancer treatment response assessment. Integrated systems are needed to support end-to-end management of response assessment data including data acquisition, analysis, and visualization. Data acquisition includes systems to acquire and store clinical images for research as well as systems to create image annotation data whether manual image annotation or automated image processing algorithms. Response calculation methods also need to be integrated with structured image annotation databases to perform data analysis to generate response interpretations. The images, image annotations, and response interpretations must be integrated with Clinical Trial Management Systems (CTMS) to enable visualization of response interpretations for treatment decision-making and auditing of clinical trial image response data.