Journal of Oncology / 2011 / Article / Tab 1

Clinical Study

The Gap between Tobacco Treatment Guidelines, Health Service Organization, and Clinical Practice in Comprehensive Cancer Centres

Table 1

According to Hughes J. R. Nicotine withdrawal symptoms. Effects of abstinence from tobacco: valid symptoms and time course.

Withdrawal SymptomsPeakDuration

Anger/irritability/frustrationWithin first week2, 4 or more weeks
Anxiety3 day2 weeks
Dysphoria (depressed mood and negative affect)1, 2, 3 weeks4 weeks
Difficulty concentrating2, 3 days3, 4 weeks
Impatience3, 4, or more weeks
Insomnia (sleep fragmentation)
Restlessness1, 3 days2, 4 weeks

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