Mitochondrial DNA Content Varies with Pathological Characteristics of Breast Cancer
Figure 2
Comparison of the mtDNA content and the T/N ratio in tumors of different grade. (a) mtDNA content of tumor tissues and their surrounding pathologically normal tissues, in tumors of different grade. (b) T/N ratio of tumors with different grade. T, mtDNA content of the tumor tissue; N: mtDNA content of the pathologically normal tissue surrounding the tumor tissue; T/N ratio: the ratio of mtDNA content of the tumor tissue to that of the pathologically normal tissue surrounding the tumors from the same individual; -axis represents tumor histological grade; the -axis represents mtDNA content (mtDNA/B2M gene) and T/N ratio respectively, in (a) and (b); the results from tumors of grades 0 and I and grade III were compared with those from tumors of grade II; The symbols * and ** represent significance value of <0.05 and <0.01, respectively.
