Journal of Oncology / 2011 / Article / Tab 1

Clinical Study

Prevalence of Epithelial Ovarian Cancer Stem Cells Correlates with Recurrence in Early-Stage Ovarian Cancer

Table 1

Patient and tumor characteristics and percentage of CD44+ EOC stem cells. Groups are classified based on their CD44 expression as tumors containing less than 20% CD44 positive (>20%) or more than 20% CD44 positive cells (<20%).

CharacteristicsNo. of patients%<20% CD44 Cells
N (%)
>20% CD44 Cells
N (%)

Age0.0013
 <50108.66 (60.0)4 (40.9)
 51–655446.240 (74.1)14 (25.9)
 >655345.351 (96.2)2 (3.8)
 Median 63.2
 Range 32–79
FIGO stage0.00025
 I1412.06 (42.9)8 (57.1)
 II119.49 (81.8)2 (18.2)
 III7059.861 (87.1)9 (12.9)
 IV2218.821 (95.5)1 (4.5)
Tumor grade0.0209
 186.84 (50.0)4 (50.0)
 24235.936 (85.7)6 (14.3)
 35849.651 (87.9)7 (12.1)
 Not graded (clear cell or metastatic biopsy)97.7
Histopathologic cell type0.0760
 Serous10085.586 (86.0)14 (14.0)
 Endometrioid54.34 (80.0)1 (20.0)
 Clear cell86.85 (62.5)3 (37.5)
 Mucinous10.90 (0.0)1 (100)
 Carcinomas
 (mixed or undifferentiated)
32.62 (66.7)1 (33.3)
Residual postoperative tumor0.014
 ≤1 cm5651.442 (75.0)14 (25.0)
 >1 cm
  (Unknown: 8 )
5348.649 (92.5)4 (7.5)
CD44 immunostaining
 Less than 20% CD44+ cells9782.9NANANA
 More than 20% CD44+ cells2017.1

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