Familial Papillary Thyroid Carcinoma: A Retrospective Analysis

Table 3

Surgical pathology results of nonfamilial and familial cases.

	Nonfamilial	1st Degree,2 members	1st Degree, 3 or more members	P value
No. of patients	521	50	41
Tumour > 3.0 cm	126 (24.2%)	12 (24.0%)	8 (19.5%)	0.61
Tumour in perithyroidal tissue/thyroid capsule penetration	87 (16.7%)	8 (16.0%)	11 (26.8%)	0.17
Multifocal disease	272 (52.2%)	31 (62.0%)	23 (56.1%)	0.34
Bilateral disease	170 (32.6%)	20 (40.0%)	16 (39.0)	0.25
Vascular/lymphatic invasion	58 (11.1%)	7 (14.0)	5 (12.2%)	0.73
Lymphocytic infiltration	215 (41.3%)	19 (38.0%)	16 (39.0%)	0.71