Journal of Oncology / 2011 / Article / Tab 4

Research Article

A Cohort Study of p53 Mutations and Protein Accumulation in Benign Breast Tissue and Subsequent Breast Cancer Risk

Table 4

p53 immunopositivity in benign breast tissue and risk of breast cancer.

VariableLevel No. of casesNo. of controls OR (95% CI)OR (95% CI)

ImmunopositiveAbsent370345 1.0 (reference) 1.0 (reference)
Present8386 0.95 (0.62–1.44) 0.88 (0.57–1.37)
Missing3840
% cells immunopositive
0370345 1.00 (reference) 1.00 (reference)
>0–<14239 1.25 (0.69–2.26) 1.27 (0.68–2.35)
1–93037 0.75 (0.40–1.39) 0.68 (0.36–1.32)
≥101110 0.74 (0.26–2.10) 0.57 (0.20–1.64)
Missing3840

Adjusted for center, age at enrollment, and years of followup.
Adjusted for age at enrollment, center (city), years of followup, histology (nonproliferative, proliferative disease), family history (no, yes), age at menarche (<12,12,13,14–19), age at first birth (continuous), number of pregnancies (continuous), and menopausal status (premenopausal, perimenopausal, postmenopausal).

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