Toll-Like Receptor 7 Agonist Therapy with Imidazoquinoline Enhances Cancer Cell Death and Increases Lymphocytic Infiltration and Proinflammatory Cytokine Production in Established Tumors of a Renal Cell Carcinoma Mouse Model
Figure 5
3M011 does not affect RCC tumor cellular proliferation. (a), (b) Immunohistochemical staining of RENCA RCC xenografts for Ki-67 cell proliferation marker following treatment 2 days prior with placebo (a) or 3M011 imidazoquinoline (b), representative examples at 100x magnification. (c) Mean percentage of tumor tissue with positive Ki67 staining 2 days after placebo versus 3M011 treatment. ‡.
