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Journal of Oncology
Volume 2012, Article ID 154303, 4 pages
Clinical Study

Update of Assessment of Survival in Head and Neck Cancer after Regional Recurrence

1Department of Head and Neck Surgery and Otorhinolaryngology of the Heliópolis Hospital, São Paulo, Brazil
2Department of Head and Neck Surgery, Hospital das Clínicas, São Paulo School of Medicine, University of São Paulo, São Paulo, Brazil

Received 29 May 2012; Revised 9 July 2012; Accepted 9 September 2012

Academic Editor: Andreas Dietz

Copyright © 2012 Ali Amar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To evaluate site of regional recurrence in patients with squamous cell carcinoma of upper aerodigestive tract after neck dissection and the results of salvage treatment. Methods. 95 patients with regional recurrence as the first manifestation of relapse were selected between 943 patients who underwent neck dissection. We evaluated level and side of recurrence, as well disease control after salvage treatment. Results. Level II was the most frequent site of recurrence. Salvage treatment was performed in 51% of ipsilateral and in 75% of contralateral (nondissected neck) recurrences. Control of the disease 12 months after salvage surgery was 25% in the ipsilateral and 37% in contralateral recurrences. Conclusions. Cervical recurrences occur predominantly in level II. Relapse in level I is frequent only in oral cavity tumors and relapse in level V is rare. The neck recurrence carries a poor prognosis even among patients who underwent retreatment with curative intent.