Review Article

Adrenocortical Carcinoma: Current Therapeutic State-of-the-Art

Table 1

Comparison UICC and ENSAT staging systems for ACC.

StageUICC/WHO 2004ENSAT 2008

IT1, N0, M0T1, N0, M0

IIT2, N0, M0T2, N0, M0

IIIT1-2, N1, M0T1-2, N1, M0
T3, N0, M0T3-4, N0-1, M0

T1–4, N0-1, M1T1–4, N0-1, M1
IVT3, N1, M0
T4, N0-1, M0

T1: tumor 5 cm; T2: tumor 5 cm; T3: tumor infiltration in surrounding tissue; T4: tumor infiltration in adjacent organs [ENSAT additionally the presence of a tumor thrombus in the Vena Cava or Vena Renalis]; N0: absence of positive lymph nodes; N1: presence of positive lymph nodes; M0: absence of distant metastases; M1: presence of distant metastasis.