Fatty Acids in Habitual Diet, Plasma Phospholipids, and Tumour and Normal Colonic Biopsies in Young Colorectal Cancer Patients
Table 2
Median (25th, 75th quartile) dietary intake of fatty acids (g/day and %) and fatty acid concentrations of plasma phospholipids (PL) (weight%), Nordic Nutrition Recommendations (NRR) and correlation between diet (g/day) and plasma PL in colorectal cancer patients ()a.
Dietary fat intake
NRR
Plasma PL (weight %)
g/day
%
Total fat
90.3 (75.7, 107.5)
33.8 (30.4, 36.9)
<30 %
Total saturated fatty acids
33.7 (28.3, 41.1)
12.9 (11.0, 14.0)
<10 %
40.2 (39.5, 40.9)
0.23
16:0 (palmitic acid)
16.9 (14.0, 19.4)
6.3 (5.4, 6.9)
27.5 (26.4, 28.9)
0.20
18:0 (stearic acid)
7.9 (6.7, 10.1)
3.1 (2.7, 3.5)
12.5 (11.9, 13.5)
−0.05
16:1-7 (palmitoleic acid)
1.6 (1.4, 1.8)
0.6 (0.5, 0.7)
0.52 (0.46, 0.69)
0.31c
18:1-9 (oleic acid)
27.3 (22.0, 32.6)
10.1 (8.5, 11.4)
8.5 (7.8, 9.4)
0.20b
20:1-9 (eicosenoic acid)
0.7 (0.6, 0.9)
0.3 (0.2, 0.3)
0.14 (0.12, 0.16)
0.12
18:2-6 (linoleic acid) (LA)
15.2 (12.1, 19.5)
5.7 (4.7, 6.7)
20.3 (17.4, 22.0)
0.10
18:3-3 (-linolenic acid (ALA)
2.1 (1.8, 2.8)
0.8 (0.7, 0.9)
0.25 (0.21, 0.30)
0.12
20:4-6 (arachidonic acid) (AA)
0.14 (0.11, 0.18)
0.05 (0.04, 0.06)
9.2 (7.9, 10.7)
0.03
20:5-3 (eicosapentaenoic acid) (EPA)
0.30 (0.21, 0.43)
0.1 (0.07, 0.18)
1.3 (1.0, 2.2)
0.21
22:6-3 (docosahexaenoic acid) (DHA)
0.50 (0.38, 0.64)
0.2 (0.13, 0.27)
5.6 (4.7, 6.9)
0.42d
Sum EPA + DHA
0.82 (0.60, 1.04)
0.3 (0.2, 0.4)
≥0.45 g/day
7.2 (5.8, 9.2)
0.36c
Ratio AA/EPA
0.42 (0.35, 0.67)
6.9 (4.8, 9.1)
0.14
Sum -3 fatty acids (ALA + EPA + DHA)
3.08 (2.55, 3.77)
1.1 (1.0, 1.3)
>1 %
7.35 (6.11, 9.38)
0.16
Sum -6 fatty acids (LA + AA)
15.37 (12.30, 19.80)
5.7 (4.8, 6.8)
30.10 (27.55, 31.65)
−0.08
Ratio -3/-6 fatty acids
0.19 (0.17, 0.23)
0.25 (0.20, 0.33)
0.29b
Total polyunsaturated fatty acids
18.4 (14.9, 23.4)
7.0 (6.0, 8.0)
5–10 %
37.7 (36.5, 39.2)
−0.16
aAbbreviations are as follows: %: percent of energy intake; NRR: Nordic Nutrition Recommendations; PL: phospholipids; : Pearson correlation coefficient.
bSignificant correlation ().
cSignificant correlation ().
dSignificant correlation ().
