The Amazing Power of Cancer Cells to Recapitulate Extraembryonic Functions: The Cuckoo's Tricks

<table><i>Evolutive phases of the  inflammatory cancer cell.</i> Cancer cells can adopt an inflammatory phenotype to invade neighboring tissues and survive in these ectopic sites. In the successive phases of tumorigenesis, the cancer cells invade the host by expressing natural and adaptive immune-related mechanisms. sc: stem cell; scc: stem cancer cell; shc: stem hematopoietic cell; f: fibroblast; mn: monocyte; mf: myofibroblast; g: granulocyte; mØ: macrophage; lc: lymphatic capillary; cc: cancer cell; lnm: lymph node metastasis; hev: high endothelial venule; l: lymphocytes; pcv: postcapillary venule; bc: blood capillary; p: pericyte; <svg height="11.525" id="M1" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 6.4749999 11.525" width="6.4749999" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
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Journal of Oncology

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Figure 2

Figure 2: The Amazing Power of Cancer Cells to Recapitulate Extraembryonic Functions: The Cuckoo's Tricks 