DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression

Table 1

Immunostaining intensity of pChk2 in ovarian serous tumors, normal ovaries, and fallopian tubes.

Staining intensity	Low-grade	High-grade	High-grade	SBT	Serous cystadenoma	Normal ovaries and FTE
	SC	SC (primary)	SC (recurrent)
0	31 (73.8%)	47 (29.6%)	28 (30.7%)	16 (100%)	10 (100%)	5 (100%)
1+	5 (11.9%)	37 (23.3%)	15 (16.5%)	0	0	0
2+	3 (7.1%)	39 (24.5%)	18 (19.8%)	0	0	0
3+	3 (7.1%)	36 (22.6%)	30 (33%)	0	0	0

SC: serous carcinoma; SBT: serous borderline tumor; FTE: fallopian tube epithelium.