Analysis on the Clinical and Pathological Features and Prognosis of Familial Gastric Cancer in South China Population: A Single-Center Study of 724 Patients

Table 1

The contrast of clinicopathological parameters between patients with familial gastric cancer (FGC) and patients with sporadic gastric cancer (SGC) (𝑛, %).

	FGC	SGC	𝑃 value
𝑛	51	673
Age (y)			0.001
≤50	26 (51.0)	193 (28.7)
>50	25 (49.0)	480 (71.3)
Gender			0.510
Male	36 (70.6)	502 (74.6)
Female	15 (29.4)	171 (25.4)
Tumor size (cm)			0.052
≤5	24 (47.1)	415 (61.7)
>5	27 (52.9)	258 (38.3)
Tumor location			0.235
Upper	8 (15.7)	126 (18.7)
Middle	6 (11.8)	113 (16.8)
Lower	19 (37.3)	280 (41.6)
Diffuse	18 (35.2)	154 (22.9)
Pathology			0.919
Differentiated	21 (41.2)	282 (41.9)
Undifferentiated	30 (58.8)	391 (58.1)
Depth of invasion			0.549
T1	7 (13.7)	119 (17.7)
T2	5 (9.8)	100 (14.9)
T3	8 (15.7)	88 (13.1)
T4a	20 (39.2)	268 (39.8)
T4b	11 (21.6)	98 (14.6)
Lymph node metastasis			0.201
N0	17 (29.3)	229 (34.0)
N1	6 (10.3)	82 (12.2)
N2	7 (12.1)	108 (16.0)
N3	28 (48.3)	254 (37.8)