Dual Roles of METCAM in the Progression of Different Cancers
Effect of overexpression of huMETCAM on tumor formation of a human melanoma cell line SB-2 . SB-2 is a human melanoma cell line, which did not express any huMETCAM. SB-2-neo is the SB-2 cells transected with the empty vector, as a negative control. MELCAM is a clone of the SB-2 cells which were transfected with huMETCAM cDNA and expressed a high level of huMETCAM. Since tumor formation was only shown in one nude mouse for each clone, statistical analysis was not possible.
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